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| For this reason, it would be prudent to avoid the concurrent use of other central nervous system depressants such as barbiturates, benzodiazepines, opiate agonists, antipsychotics, tricyclic antidepressants, ethanol, other antihistamines, sedatives, and hypnotics. | This drug combination should be avoided, if possible, as other antimanic or antihypertensive agents are available. | Ask a doctor or pharmacist if the medication dose should be gradually tapered down to avoid these safety and efficacy of duloxetine, bupropion, maprotiline, mirtazapine, nefazodone, and trazodone have not been established in children younger than 18 years. |
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